Translational Research and Validation

The CRF Skirball Center for Innovation (SCI) is more than just a state-of-the-art translational research facility. We inhabit a unique niche by providing services that go well beyond conventional models of research. Our experience and expertise can be harnessed at any stage in a product’s life cycle:

• For consultation on your entire preclinical and clinical research strategy with a focus on safe and effective human application
• To devise customized and unique research approaches and models to optimize the development progress
• To develop a strategy and provide a platform for sharing and publicizing key data

Regulatory Science

Our regulatory expertise is an integral part of the innovation and development process. Everything at the CRF Skirball Center for Innovation (SCI) is planned, designed and executed with the ultimate goal of transitioning your technology to human application.

Partnering with us allows you to optimize the entire development process so that you can plan for and meet established milestones. Customized research approaches and models are created in collaboration with regulatory bodies to answer relevant questions faster and more efficiently.

SCI meets the highest regulatory standards. We are accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC), as well as compliant with the Office of Laboratory Animal Welfare (OLAW) and Good Laboratory Practices (GLP) regulations. These guidelines govern non-clinical studies and ensure the quality, integrity, and reliability of study data.

Early Human Application

The CRF Skirball Center for Innovation (SCI) has a strong track record of success in advancing technologies and treatments from translational research performed in its preclinical laboratories to first-in-human trials. Once safety and feasibility are proven in preclinical studies, we can effectively transition your technology into first-in-human trials through our international network of experienced clinical research centers. Our physician leaders remain involved throughout the process by providing their insight and experience gained during animal testing to the training and guidance of local physician investigators.

Thanks to this unique model of advancing medical innovation worldwide, over 20 different technologies evaluated at SCI have reached the first-in-man phase or received a CE Mark, IDE or FDA market clearance since our opening in 2005.

Physician Feedback, Training And Education

We believe in the paramount role that rigorous research, feedback and education play in the innovation process. The cycle of innovation at the CRF Skirball Center for Innovation (SCI) continues by collecting invaluable feedback and input from our in-house physicians and external key opinion leaders, and using it to improve and advance the development of your technology.

We are also committed to educating the next generation of physicians in this rapidly progressing field of minimally invasive catheter based therapies. SCI is uniquely equipped for physician training and education. We can provide hands-on experience and virtual training through our animal and benchtop laboratories and meeting rooms with global broadcasting capabilities.