Peripheral Artery Disease

Peripheral artery disease (PAD)—sometimes called peripheral vascular disease—encompasses a variety of diseases which affect the blood supply to the limbs. PAD may cause pain while walking or exercising, as well as a feeling of numbness or tingling in the legs. Smoking or having high cholesterol, high blood pressure, or diabetes increases the risk of developing PAD. Underdiagnosed and undertreated, PAD affects over 8.5 million Americans.

Sometimes behavioral changes or medications can improve PAD symptoms, but when these treatments are not enough, angioplasty with a balloon or a special kind of stent made just for leg arteries may help open blockages.

CRF is involved in evaluating and improving a variety of interventional therapies for PAD, including drug coated balloons, new stent designs, and distal embolic protection devices.

Relevant CTC Service Areas for Peripheral Artery Disease

• Trial Design
• Protocol Development
• Data Management
• Statistics And Programming
• Angiographic Core Lab
• CEC
• DSMB
• Medical Writing
• Extended Database Management and Analysis

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