Clear Thinking. Clear Value.

Advancing Patient Care With World-Class Clinical Research

Over 60 manuscripts since 2015 from PARTNER I and PARTNER II, including landmark papers in The New England Journal of Medicine, JAMA, and The Lancet.

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The JETSTREAM Calcium study showed increased lumen dimensions by IVUS in femoral-popliteal lesions by removing superficial calcium with the Jetstream Atherectomy System without major complications.

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The CRF Publications Office has published over 300 papers since 2007 from ACUITY, HORIZONS-AMI, INFUSE-AMI, PROSPECT, and other studies.

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HORIZONS-AMI investigators found that sustained ventricular tachycardia/fibrillation after primary PCI was not significantly associated with 3-year mortality or major adverse clinical events.

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NIRS imaging used to detect lipid core containing plaque in the CANARY, YELLOW, and COLOR studies was analyzed at the CRF IVI Core Lab.

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PARTNER investigators found that the relationship between moderate/severe pulmonary hypertension and increased mortality after TAVR is altered by sex, and clinical factors appear to be more influential in stratifying risk than hemodynamic indices.

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In the HORIZONS-AMI trial, the development of new-onset congestive heart failure within 2 years after contemporary PCI, although infrequent, was associated with significantly increased rates of mortality and major adverse ischemic events.

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Why Us?

  • The CTC offers a unique combination of services that focus on improving cardiovascular outcomes through the design and execution of clinical trials that investigate innovative therapies
  • Scientific leadership with unparalleled expertise
  • Experience in planning and overseeing some of the most influential clinical trials in interventional cardiology
  • Strategic partnerships that guide promising ideas to the marketplace at all stages of a company life cycle, from the smallest of start-ups to the largest NASDAQ-listed players
  • Scientifically robust state-of-the-art core labs
  • Regulatory experience, including numerous presentations to the FDA
  • A committed operations team, in addition to comprehensive and sophisticated evaluation and analysis services
Key Statistics:
  • CTC has been involved in over 700 clinical trials, amassing data on more than 200,000 patients
  • More than 100 active projects
  • Strong relationships with over 130 sponsors and institutions
  • Conducts image analyses of more than 10,000 subjects per year
  • Adjudicates over 3,000 clinical events and endpoints per year

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To find out more about CRF Clinical Trials Center and how we can best serve your needs.