Our History

Careers

Our History

For over 20 years, Skirball Center for Innovation has contributed to key advances in the treatment of cardiovascular disease and played an essential role in bringing innovative new technologies, pharmacologic therapies, and treatment paradigms to patients.

  • The CRF Skirball Center for Innovation opens.
  • The first physician training is held.
  • The inaugural first-in- man study is performed using technology whose key preclinical testing was performed at the CRF Skirball Center for Innovation.
  • The first live broadcast of investigational technology is transmitted to the Main Arena at TCT.
  • The first Good Laboratory Practices (GLP) study is performed.
  • The CRF Skirball Center for Innovation core imaging laboratory opens.
  • The first IDE is granted based predominantly on GLP studies performed at the CRF Skirball Center for Innovation.
  • A landmark paper published by Murata validates the utility of optical coherence tomography (OCT) in the evaluation of stents.
  • The first report is published on the use of the familial hypercholesterolemic (Rapacz) swine in testing of coronary drug-eluting stent efficacy.
  • The first report is published on the predictive value of the familial hypercholesterolemic (Rapacz) swine in assessing the efficacy of drug-coated balloons.
  • The first FDA market approval is granted for a technology whose key preclinical testing was performed entirely at the CRF Skirball Center for Innovation.
  • FDA audit of the CRF Skirball Center for Innovation concludes with no deficiencies noted.
  • The CRF Skirball Center for Innovation hosts an exclusive Skirball Symposium on drug-coated balloon technologies.
  • A total of 20 different technologies evaluated preclinically at the CRF Skirball Center for Innovation have reached the first-in-man phase or received CE Mark, IDE, or FDA market clearance.
  • The CRF Skirball Center for Innovation surpasses 100 abstracts presented at interventional cardiology conferences worldwide
  • The CRF Visual Interactive Technology Center (VITC) is launched at TCT 2014.
  • The inaugural CRF Interventional Innovation Award is presented at TCT 2014. The winning technology was chosen from more than 50 entries
  • The CRF Skirball Center for Innovation celebrates its 10-year Anniversary.
  • CRF Skirball Center for Innovation conducts physician training immediately preceding first-in-man applications.
  • The Visual Interactive Training Center is renamed Interactive Training Center for remote (virtual) and in-person physician and allied healthcare personnel training sessions
  • The CRF Skirball Center for Innovation gathers a group of worldwide experts to vet novel technologies in the first-ever Innovation Shark Tank competition at TCT 2015.